张建珍:女,1971年生,山西五台人。理学博士,bt365手机客户端教授、博士生导师。
联系方式:
电话:0351-7018871
地址:山西省太原市坞城路92号,bt365手机客户端 030006
学历背景:
1990年9月-1994年7月:山西农业大学动物医学系公共卫生专业本科生,获学士学位
1994年9月-1997年7月:扬州大学动物医学系微生物学专业研究生,获硕士学位
2001年9月-2006年7月:山西大学生命科学学院研究生,获博士学位
2003年10月-2003年11月:中科院遗传所进修学习
2008年2月-2009年6月:美国堪萨斯州立大学博士后
学术简介:
近几年的主要研究方向:1)昆虫表皮代谢的分子生物学;2)基于RNAi的害虫防治研究;3)昆虫农药代谢与分子毒理学
近5年来主持国家自然科学基金面上项目、承担国家973项目骨干课题和国家自然科学基金国际重大合作项目等十多个科研项目。
获奖:
2012年10月入选太原市科技拔尖人才计划
2011年12月遴选为山西大学青年英才
2011年6月遴选为山西省优秀青年学术带头人
2008年9月获得山西省青年科技奖
近期科研项目:
1. 参与973项目2012CB114102“害虫种群暴发的行为遗传机制”(2012.1-2016.8)
2. 主持国家自然科学基金项目
31272380 “飞蝗几丁质酶基因家族的功能及激素调控机制研究”
(2013.1-2016.12)
4. 主持山西省农业攻关项目 20110311010“基于RNAi的害虫杀虫基因筛选及转基因抗虫作物新品系研发”(2011.1-2013.12)
5. 主持完成国家自然科学基金项目30970410 “东亚飞蝗几丁质合成酶的特性及其在几丁质合成抑制中的功能研究”(2010.1-2012.12)
6. 参与国家自然科学基金重大国际合作与交流项目31320103921“飞蝗细胞色素P450单氧化酶基因代谢解毒、生理功能及分子调控”(2014.1-20118.12)
近年发表的主要研究论文:
2. Zhang J.Q., Li D.Q., Ge P.T., Yang M.L., Zhu K.Y., Guo Y.P., Ma E.B. and Zhang J.Z. 2013. RNA interference revealed the roles of two carboxylesterase genes in insecticide detoxification in Locusta migratoria,Locusta migratoria. Chemosphere
doi: 10.1016/j.chemosphere.2013.06.081
3. Rong S., Li D.Q., Zhang X.Y., Li S., Zhu K.Y., Guo Y.P., Ma E.B. and Zhang J.Z. 2013. β-N-acetylglucosaminidase gene is essential for larval-larval and larval-adult molting in Locusta migratoria. Insect science, 20:109-119
4. Wang YL, Yang ML, Jiang F, Zhang JZ, Kang L. 2013. MicroRNA-dependent development revealed by RNA interference-mediated gene silencing of LmDicer1 in the migratory locust Insect science, 20:53-60
5. Qin G.H., Jia M., Liu T., Zhang X.Y., Guo Y.P., Zhu K.Y., Ma E.B., Zhang J.Z. 2013. Characterization and functional analysis of four glutathione S-transferases from the migratory locust, Locusta migratoria. PLoS ONE 8 (3) : e58410
7. Zhang X.Y., Li T., Zhang J.Q., Li D.Q., Guo Y.P., Qin G.H., Zhu K.Y., Ma E.B. and Zhang J.Z. 2012. Structural and catalytic role of two conserved tyrosines in Delta class glutathione S-transferase from Locusta migratoria Archives of Insect Biochemistry and Physiology, 80:77-91
8. Qin G.H., Liu T., Jia M., Zhang X.Y., Guo Y.P., Zhu K.Y., Ma E.B., and Zhang J.Z. Heterologous expression and characterization of a sigma glutathione S-transferase involved in carbaryl detoxificationfrom oriental migratory locust, Locusta migratoria manilensis (Meyen) Journal of Insect physiology, 2012, 58:220-227
9. Zhang J.Z., Zhang X., Arakane Y., Muthukrishnan S., Kramer KJ., Ma EB. and Zhu K.Y. 2011. Comparative genomic analysis of chitinase and chitinase-like family in the African Malaria Mosquito (Anopheles gambiae) PLoS ONE. 6:e19899
10. Zhang J.Z., Zhang X., Arakane Y., Muthukrishnan S., Kramer K.J., Ma E.B. and Zhu K.Y. 2011. Identification and characterization of a novel chitinase gene cluster (AgCht5) possibly derived from tandem duplications in the African malaria mosquito, Anopheles gambiae.Insect Biochemistry and Molecular Biology, 2011(41):521-528.
11. Zhang J.Z.,Liu X.J., Zhang J.Q., Li D.Q., Sun Y., Guo Y.P., Ma E.B. and Zhu K.Y. 2010. Silencing of two alternative splicing-derived mRNA variants of chitin synthase 1 gene by RNAi is lethal to the oriental migratory locust.Insect Biochemistry and Molecular Biology, 40:824-833
12. Zhang J.Z. and Zhu K.Y. 2006. Characterization of a chitin synthase cDNA and its increased mRNA level associated with decreased chitin synthesis in Anopheles quadrimaculatus exposed to diflubenzuron. Insect Biochemistry and Molecular Biology, 36: 712-725.
13. Zhang J.Z., Zhang J.Q, Yang M.L, Jia Q.D.,Guo Y.P., Ma E.B. and Zhu K.Y. 2011. Genomics-based approaches to screening carboxylesterase genes potentially involved in malathion resistance in oriental migratory locust (Locusta migratoria manilensis) Pest Management Science, 67:183-190
14. Qin G.H., Jia M., Liu T., Xuan T., Zhu K.Y., Guo Y.P., Ma E.B. and Zhang J.Z. 2011. Identi?cation and characterization of ten glutathione S-transferase genes from oriental migratory locust, Locusta migratoria manilensis (Meyen) Pest management science, 67:697-704
15. Yang M.L., Yin K., Guo Y.P., Ma E.B. and Zhang J.Z. 2011.A Photosensitivity Insecticide, 5-Aminolevulinic Acid, Exerts Effective Toxicity to Oxya chinensis (Orthoptera: Acridoidea). Agricultural Sciences in China, 10:101-105
16. Guo Y.Q., Zhang J.Z., Yang M.L., Yan LZ, Zhu Y.K., Guo Y.P. and Ma E.B. 2012. Comparative analysis of cytochrome P450-like genes from Locusta migratoria manilensis: expression profiling and response to insecticide exposure. Insect science, 19 (75-85) (SCI)
17. Guo Y.Q., Zhang J.Z., Yu R.R., Zhu Y.K., Guo Y.P. and Ma E.B. 2012. Identification of two new cytochrome P450 genes and RNA interference-based approaches to evaluate their roles in detoxification of commonly used insecticides in the migratory locust. Chemosphere. 87:709-717
18. Zhang J.Z.,Zhang J.Q., Yang M.L, Qin G.H., Li D.Q.,Guo Y.P., Ma E.B. and Zhu K.Y. 2011. Research progress in understanding insecticide resisitance in oriental Migratory Locust, Locusta migratoria manilensis. Resistant Pest Management Newsletter 20:51-53
授权发明专利:
发明人,专利名称,授权时间,授权国别,专利号
1)张建珍,李大琪,张建琴,马恩波,郭亚平,杨美玲,昆虫几丁质酶基因及其dsRNA的应用,2011.8,中国,ZL 2010 1 0136330.5
2)张建珍,杨美玲,李大琪,马恩波,稻蝗属特异性分子标记DNA序列及其应用,2011.5, 中国,ZL 2009 1 0263932.4
3)张建珍,刘晓健,马恩波,杨美玲,郭亚平,一种昆虫几丁质合成酶1基因片段及其dsRNA和应用,2011.9,中国,ZL 2010 1 0163625.1
4)张建珍,刘晓健,马恩波,郭亚平,张建琴,一种昆虫几丁质合成酶2基因和应用,2012.1,中国,ZL 2010 1 0163618.1
5)张建珍,刘晓健,马恩波,杨美玲,郭亚平,昆虫几丁质合成酶1基因片段及其dsRNA和应用,2012.1,中国,ZL 2010 1 0163607.3
6)郭亚平,张建珍,刘晓健,马恩波,李大琪,一种昆虫几丁质合成酶1A基因片段及其dsRNA和应用,2011.9,中国,ZL 2010 1 0163645.9
7)刘晓健 ,张建珍,杨美玲,马恩波,郭亚平,一种昆虫几丁质合成酶1B基因片段及其dsRNA和应用,2012.1,中国,ZL 2010 1 0163634.0